Neurons and the endocannabinoid system (ECS)

The endocannabinoid system is found in every system of the body. Its main goal is to help the body achieve homeostasis, or perfect cellular balance. The majority of cannabinoid receptors – subtype 1 (CB1) are found in the central and peripheral nervous systems. They are located on nerve cells called neurons. We have recently learned that some CB2 receptors also express in these areas but expression is limited. So let’s talk a little bit about neurons.

Neurons – Are the primary signaling cells of the central nervous system (CNS).

There are three distinct classes of neurons.

  1. Sensory neurons – These neurons tell the body what’s going on outside, sensing signals from the outside world and sending that information back inside the body.
  2. Motor neurons – These neurons convey commands to move muscles, or give instructions to glands and organs.
  3. Interneurons – They are only found in the CNS. They connect one neuron to another, and receive information from other neurons of multiple form and type. Interneurons process multiple types of information both through simple and complex circuits.

Scientists have learned that many times the cannabinoid receptors co-express with other receptors. They create a cross talk (communicate with each other) to help the body signal more effectively. If is for this reason that we talk a lot about the different receptors, where and how they express, and the many different messengers that are capable of signaling within this system. When we know these things we know better how to use specific messengers such as cannabinoids, terpenes, essential oils, and vital nutrients that all work to assist signaling.


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