The PPARγ receptor is a nuclear receptor and is located within the nucleus of the cell. The receptor’s job is to regulate fatty acid storage and glucose metabolism. PPARγ communicates with fat cells and sends the cells messages to grow and or expand. The body is told to create fat cells or process the fat into energy to fuel other body processes. So one great way to target fat cells, and the way your body talks to these fat cells is to look into targeting the PPARγ receptor.
The terpene chamazulene is a messenger to the PPARγ receptor and can act on the receptor in a number of different ways. One way is that it can help to block the over-expression of fat cells. By supporting PPAR, the receptor sends information to the genes that drive fat production also called lipogenesis. Next we know this receptor is responsible for fatty acid storage but what is a fatty acid? Fatty acids are the building blocks of fat. When we consume fats the body works to break them down to their basic fatty acids, which it can use in glucose metabolism. If there is no glucose available, the body can use fatty acid stores for fuel. This is also the premise for ketosis and a ketogenic diet wherein the body runs on fats instead of glucose.
Additionally we know that the cannabinoid receptors are expressed in fat cells. High levels of CB1 can contribute to driving the fat expansion process.
Chamazulene again is a great messenger to target the PPARγ receptor and is found in very high levels in blue tansey and in Yarrow Pom. The dōTERRA yarrow pom is also in pomegranate seed oil which help to increase bioavailability.
Learn what you can do to help feed and support your PPARγ receptor, so that you can gain some wonderful benefits for a more healthy you.
- Chamazulene is a main constituent in Blue Tansy essential oil
- dōTERRA’s Yarrow Pom contains Chamazulene
- Chamazulene Acts on the PPARγ receptor.
- PPARγ regulates fatty acid storage and glucose metabolism, this is important when dealing with inflammation.
- The PPARγ receptor is part of the larger integrated endocannabinoid system.