Did you know you are hard-wired for cannabinoids?

Did you know that you are hardwired to benefit from cannabinoids? The most important thing to know is, if your system is damaged or deficient, you may not get the benefits your body needs. Your body also creates cannabinoids called (endo)cannabinoids – endo, or inside. They are actually created by your body. They are intelligent molecules that hold vital information for your cells. The body actually produces 6 endocannabinoids. The two most well known endocannabinoids are Anandamide and 2-AG. I bet you thought they were the only ones…..nope.

 
The Six Endocannabinoids
 
1. N-Arachidonoylethanolamide “Anandamide” (AEA)
2. 2-Archidonoylglycerol (2-AG)
3. 2-Archidonoylglycerol ether (noladin ether)
4. O-Arachidonoyl ethanolamine (virodhamine)
5. N-Arachidonoyl dopamine (NADA)
6. N-palmitoylethanolamide (PEA).
As of 2017, N-palmitoylethanolamide (PEA), has been added to the list of endogenous cannabinoids (Musella, A. et al., 2017). Now the 6th endocannabinoid. 
 

What is important to understand is that no molecule can get its message to a cell unless the cell has a receptor for that specific messenger. The message will just fall on deaf ears and go unnoticed. Each of the endocannabinoids above has a specific target to relay its cellular information. If those receptors are not expressed in a balanced and sufficient way, the messages can become disruptive and even work against the body. It’s not enough to just blindly consume cannabis and believe it will yield magical benefits. The ECS does not work that way. Yes it is intelligent, and yes it is going to constantly work to help your body reach a dynamic balance, but sometimes this takes some effort or action on your part so that the system re-aligns and regains its proper heading.

9 Responses

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